Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3855
Gene Symbol: KRT7
KRT7
0.040 GeneticVariation disease BEFREE Adult inpatients (<i>n</i> = 166) with longstanding DSM-IV Anorexia Nervosa, Bulimia Nervosa (BN) or Eating Disorder not Otherwise Specified (EDNOS) completed the CET instrument, Eating Disorder examination questionnaire (EDE-Q), Beck Depression Inventory-II (BDI-II) and Symptom checklist-90 (SCL-90). 31695652 2019
Entrez Id: 51540
Gene Symbol: SCLY
SCLY
0.040 GeneticVariation disease BEFREE Adult inpatients (<i>n</i> = 166) with longstanding DSM-IV Anorexia Nervosa, Bulimia Nervosa (BN) or Eating Disorder not Otherwise Specified (EDNOS) completed the CET instrument, Eating Disorder examination questionnaire (EDE-Q), Beck Depression Inventory-II (BDI-II) and Symptom checklist-90 (SCL-90). 31695652 2019
Entrez Id: 6886
Gene Symbol: TAL1
TAL1
0.040 GeneticVariation disease BEFREE Adult inpatients (<i>n</i> = 166) with longstanding DSM-IV Anorexia Nervosa, Bulimia Nervosa (BN) or Eating Disorder not Otherwise Specified (EDNOS) completed the CET instrument, Eating Disorder examination questionnaire (EDE-Q), Beck Depression Inventory-II (BDI-II) and Symptom checklist-90 (SCL-90). 31695652 2019
Entrez Id: 100653365
Gene Symbol: BED
BED
0.020 Biomarker disease BEFREE Balanced sporting activity should be considered a resource in the treatment of eating disorders (ED), in particular of the BED and in obesity but also, if conducted and guided by expert preparers and rehabilitators, in some forms of anorexia and in bulimia.</p> Objective: However, when physical activity becomes compulsive, an end in itself and which interferes predominantly in daily activities, aimed essentially at energy consumption to force weight loss up to marked decay, it becomes a pathological instrument, an elimination course, a form purging and falls within the diagnostic criteria in bulimia and anorexia nervosa. 31684854 2020
Entrez Id: 2875
Gene Symbol: GPT
GPT
0.010 Biomarker disease BEFREE Anorexia and bulimia nervosa are associated with poor periodontal condition, elevated salivary concentrations of total protein, AST, ALT, and LDH, decreased salivary flow rate and a significant adverse impact on OHRQoL. 31361025 2019
Entrez Id: 100653365
Gene Symbol: BED
BED
0.020 GeneticVariation disease BEFREE The 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions-III (N=36,309) included respondents who met the criteria for specific lifetime DSM-5 EDs and answered questions regarding help-seeking for their ED symptoms (anorexia nervosa [AN]: n=275; bulimia nervosa [BN]: n=91; and binge-eating disorder [BED]: n=256). 31324401 2019
Entrez Id: 5697
Gene Symbol: PYY
PYY
0.030 Biomarker disease BEFREE In studies of biological correlates, women with purging disorder demonstrated significantly greater postprandial increases in the satiety peptide, peptide tyrosine tyrosine, compared to women with bulimia nervosa and controls, and these differences predicted greater gastrointestinal distress in purging disorder. 31306252 2019
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.070 Biomarker disease BEFREE <b>Approach:</b> To test the hypothesis that treatment with OLB together with exercise vs. exercise alone would induce feedback action of GH, pancreatic polypeptide (PP), peptide tyrosine tyrosine (PYY), and leptin on ghrelin in Czech women with BN and in healthy-weight Czech women (HW). 30915029 2019
Entrez Id: 5697
Gene Symbol: PYY
PYY
0.030 Biomarker disease BEFREE <b>Approach:</b> To test the hypothesis that treatment with OLB together with exercise vs. exercise alone would induce feedback action of GH, pancreatic polypeptide (PP), peptide tyrosine tyrosine (PYY), and leptin on ghrelin in Czech women with BN and in healthy-weight Czech women (HW). 30915029 2019
Entrez Id: 26681
Gene Symbol: OR4G1P
OR4G1P
0.010 Biomarker disease BEFREE <b>Approach:</b> To test the hypothesis that treatment with OLB together with exercise vs. exercise alone would induce feedback action of GH, pancreatic polypeptide (PP), peptide tyrosine tyrosine (PYY), and leptin on ghrelin in Czech women with BN and in healthy-weight Czech women (HW). 30915029 2019
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.010 Biomarker disease BEFREE <b>Approach:</b> To test the hypothesis that treatment with OLB together with exercise vs. exercise alone would induce feedback action of GH, pancreatic polypeptide (PP), peptide tyrosine tyrosine (PYY), and leptin on ghrelin in Czech women with BN and in healthy-weight Czech women (HW). 30915029 2019
Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
0.070 Biomarker disease BEFREE This suggests that bulimia nervosa may be effectively treated with CBT-T in the context of gender dysphoria. 30843609 2019
Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
0.070 Biomarker disease BEFREE Adolescents (N = 110) were randomly assigned to FBT-BN or CBT-A and completed assessments of eating pathology and OC-ED behaviour. 30734406 2019
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.070 Biomarker disease BEFREE Neuroendocrinology of reward in anorexia nervosa and bulimia nervosa: Beyond leptin and ghrelin. 30395874 2019
Entrez Id: 4170
Gene Symbol: MCL1
MCL1
0.030 GeneticVariation disease BEFREE Ninety-four female adolescent inpatients with restricting anorexia nervosa (AN-R), 67 with binge/purge AN (AN-B/P), and 48 with bulimia nervosa (BN) were assessed on admission and discharge using the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Yale-Brown-Cornell Eating Disorders Scale (YBC-EDS), Eating Attitude Test-26 (EAT-26), Beck Depression Inventory (BDI), and State-Trait Anxiety Inventory (STAI). 30198142 2019
Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
0.070 Biomarker disease BEFREE The aim of this study was to provide an update of the most recent (since January 2014) enhanced cognitive behavioural therapy (CBT-E) effectiveness studies (randomized controlled trials and open trials) on bulimia nervosa, binge eating disorder and transdiagnostic samples. 30188385 2018
Entrez Id: 6462
Gene Symbol: SHBG
SHBG
0.010 GeneticVariation disease BEFREE Forty-six women with bulimia nervosa (BN), 31 with eating disorder not otherwise specified, purging type (EDNOS P) and 56 matched healthy controls were studied with respect to serum testosterone (T), 5alpha-dihydrotestosterone (DHT), sex hormone-binding globulin (SHBG), deyhydroepiahndrosterone sulfate (DHEAS) and luteinizing hormone (LH) and to ovarian morphology. 30172682 2019
Entrez Id: 4170
Gene Symbol: MCL1
MCL1
0.030 Biomarker disease BEFREE EAT-26 test was used to screen classic eating disorders (anorexia and bulimia). 30080233 2018
Entrez Id: 1312
Gene Symbol: COMT
COMT
0.060 Biomarker disease BEFREE The results taken together suggest that COMT genetic variability may contribute to general psychopathological symptoms in patients with BN. 29879886 2018
Entrez Id: 51540
Gene Symbol: SCLY
SCLY
0.040 Biomarker disease BEFREE There were significant differences in the global indices of the SCL-90R inventory between the three ED groups (Anorexia Nervosa (AN), Bulimia Nervosa (BN) and binge-eating disorder; ANOVA-p < 0.05). 29879886 2018
Entrez Id: 6886
Gene Symbol: TAL1
TAL1
0.040 Biomarker disease BEFREE There were significant differences in the global indices of the SCL-90R inventory between the three ED groups (Anorexia Nervosa (AN), Bulimia Nervosa (BN) and binge-eating disorder; ANOVA-p < 0.05). 29879886 2018
Entrez Id: 3855
Gene Symbol: KRT7
KRT7
0.040 Biomarker disease BEFREE There were significant differences in the global indices of the SCL-90R inventory between the three ED groups (Anorexia Nervosa (AN), Bulimia Nervosa (BN) and binge-eating disorder; ANOVA-p < 0.05). 29879886 2018
Entrez Id: 4170
Gene Symbol: MCL1
MCL1
0.030 Biomarker disease BEFREE Data were collected from 1,147 female undergraduate students (89% Kuwaiti nationals) recruited from Kuwait University through employment of the eating attitude test (EAT-26) together with an anonymous, self-administered questionnaire to determine the prevalence of symptomatology indicative of anorexia nervosa and bulimia nervosa. 29488236 2018
Entrez Id: 1815
Gene Symbol: DRD4
DRD4
0.050 GeneticVariation disease BEFREE Certain combinations of DRD4 variants may contribute to psychopathological features in BN patients. 29455021 2018
Entrez Id: 6886
Gene Symbol: TAL1
TAL1
0.040 GeneticVariation disease BEFREE Two-hundred-and-seventy-three ED patients [199 with Anorexia Nervosa (AN) and 74 with Bulimia Nervosa (BN)] completed the SCL-90R inventory and were genotyped for four functional, clinically relevant DRD4 polymorphisms: three variants in the promoter region [120-bp tandem repeat (TR, long vs. short allele), C-616G and C-521 T] and a variable number of tandem repeats (VNTR) in exon 3 (7R vs. non-7R allele). 29455021 2018